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Review

Primates and Rodent Models for Dementia: A Review

1★, 1, 1, 1★ Corresponding author

  1. 1Department of Pharmacology, Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial (ASBASJSM) College of Pharmacy, Bela, Ropar, Punjab, INDIA.

CORRESPONDENCE

Rahul Kumar Sharma

Department of Pharmacology, Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial (ASBASJSM) College of Pharmacy, Bela, Ropar, Punjab, INDIA.

buntyrahul177@gmail.com

Received: 10-06-2021; Revised: 30-06-2021; Accepted: 25-07-2021.

Volume 11, Issue 3 · pp. 254-259 · 2021 · DOI: 10.5530/ijpi.2021.3.45

ABSTRACT

Memory and cognitive functions are some of the most important and complex functions performed by the human brain. Any disorders which affect our memory will very much affect our lifestyle. Dementia and other cognitive dysfunctions are progressively emerging in the human race. To uncover newer drugs to cure such disorders we need better medium to understand the pathophysiological events occur during such disorders, so that we can make better approaches toward the cure. For such purpose different animal models are there. This review will uncover the most significant animal models. A thorough and critical evaluation of present rodent and primate models, their possible mechanism to cause such disorders and their role in drug discovery has been carried out. There are many possible pathological events that occur during cognitive disorders; in this review, we try to cover them all. This review will give a complete in-site of prognosis, progression, and evaluation of newer drugs has been made.

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    Sharma, R. K., Singh, H., Kaur, D., & Kumar, Y. (2021). Primates and Rodent Models for Dementia: A Review. International Journal of Pharmaceutical Investigation, 11(3), 254-259. https://doi.org/10.5530/ijpi.2021.3.45

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    © 2021 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. CC BY-NC-SA 4.0