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Threatened Ayurvedic Herb (Seeta Ashoka) Substitution Options for Menorrhagia-based on Bioactive Principle’s Molecular Docking Study

1★, 2, 3, 4★ Corresponding author

  1. 1Gram Mooligai (Village herbs) Co. ltd. (GMCL), Durg, Chhattisgarh, INDIA.
  2. 2Govt. S. D. S. college, Jamgao-R, Durg, Chhattisgarh,, INDIA.
  3. 3Bharati Vidyapeeth Ayurveda College, Pune, Maharashtra, INDIA.
  4. 4Tilak Ayurveda College, Pune, Maharashtra, INDIA.

CORRESPONDENCE

Utkarsh Ghate

Gram Mooligai (Village herbs) Co. ltd. (GMCL), Durg, Chhattisgarh, INDIA.

ughaate@gmail.com

Received: 09-03-2022; Revised: 23-04-2022; Accepted: 22-06-2022.

Volume 12, Issue 3 · pp. 250-254 · 2022 · DOI: 10.5530/ijpi.2022.3.45

ABSTRACT

Molecular docking studies are used to identify cultivated/ abundant herbs such as Coriander, Burmuda grass or Asparagus as potential replacement for Seeta Ashoka- Saraca asoca (Roxb.) De Wilde, syn. S. indica Linn. a rare Indian medicinal forest plant, threatened with extinction due to over harvest. Its bark is used to make the famous Ayurvedic medicine “Ashokarishta” to treat menorrhagia and as a uterine tonic like ergot but is mostly adulterated. We tested using molecular docking studies Quercetin and other polyphenols from Coriander as potent anti-inflammatory ingredients, similar to NSAID (Non-steroidal anti-inflammatory drugs)., Polyalthia longifolia, the common adulterant is also be noted to be effective as its bark contains 30-50% of tannin than Saraca asoca, so may help in thrombosis.

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    Ghate, U., Kulkarni, H., Deshpande, M., & Akkalkotkar, M. (2022). Threatened Ayurvedic Herb (Seeta Ashoka) Substitution Options for Menorrhagia-based on Bioactive Principle’s Molecular Docking Study. International Journal of Pharmaceutical Investigation, 12(3), 250-254. https://doi.org/10.5530/ijpi.2022.3.45

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    © 2022 Author(s)

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