Volume 2, Issue 4

Pranav Patel, Hitesh Patel, Shital Panchal, Tejal Mehta

pp. 169-175 · DOI: 10.4103/2230-973X.106981 · 2013

Tacrolimus (FK 506) is a potent macrolide lactone immunosuppressive agent used for prophylaxis of organ rejection after transplantation and graft‑versus‑host disease after bone marrow transplantation in patients. Moreove…

Shailesh T Prajapati, Anant P Mehta, Ishan P Modhia, Chhagan N Patel

pp. 176-182 · DOI: 10.4103/2230-973X.106988 · 2013

Purpose: The purpose of this research work was to formulate raft‑forming chewable tablets of H2 antagonist (Famotidine) using a raft‑forming agent along with an antacid‑ and gas‑generating agent.Materials and Methods: Ta…

Amish Ashvinkumar Dangi, Prakash Bhikhabhai Zalodiya

pp. 183-188 · DOI: 10.4103/2230-973X.106989 · 2013

Purpose: The demand for melt-in-mouth tablets (MMTs) has been rapidly growing during the last decade, especially for the elderly and children who have swallowing difficulties, to avoid first-pass metabolism and quick dru…

Kevin Garala, Jaydeep Patel, Anjali Patel, Mihir Raval, Abhay Dharamsi

pp. 189-200 · DOI: 10.4103/2230-973X.106996 · 2013

Purpose: The purpose of the present investigation was to improve the flow and mechanical properties of racecadotril by a crystallo‑co‑agglomeration (CCA) technique. Direct tableting is a requirement of pharmaceutical ind…

SB Shirsand, MS Para, D Nagendrakumar, KM Kanani, D Keerthy

pp. 201-207 · DOI: 10.4103/2230-973X.107002 · 2013

Purpose: Niosomes play an increasingly important role in drug delivery as they can reduce toxicity and modify pharmacokinetic and bio-availability. Topically applied niosomes can increase the residence time of drugs in t…

Mayur Desai, Rishad R Jivani, Laxman D Patel, Noordin P Jivani, Bhavin Sonagara

pp. 208-212 · DOI: 10.4103/2230-973X.107005 · 2013

Introduction: A tablet system consisting of cores coated with two layers of swelling and rupturable coatings was prepared and evaluated as time controlled chronomodulated tablet. Materials and Methods: Cores containing M…

Thakur Prasad Chaturvedi, Ruchi Srivastava, Anand Kumar Srivastava, Varun Gupta, Pushpendra Kumar Verma

pp. 213-217 · DOI: 10.4103/2230-973X.107007 · 2013

Aim: Prevention of periodontal disease progression is the primary goal of periodontal therapy. When conventional therapy is found to be inadequate in achieving periodontal health in chronic periodontitis, local antimicro…

Viroj Wiwanitkit

pp. 218 · DOI: 10.4103/2230-973X.107008 · 2013

The editorial on delivery of nutraceuticals using nanotechnology is very interesting.[1] As noted, successful formulation of new nanosubstance is the hope. However, the effectiveness and safety is still the consideration…