Volume 1, Issue 3

Javed Ali

pp. 129-130 · DOI: 10.4103/2230-973X.85960 · 2011

Plagiarism is a major threat to the integrity and grace of publication. Plagiarism could be intentional or unintentional. Intentional plagiarism usually occurs when the concerned author(s) will be benefitted by some acad…

Uday Venkat Mateti, Nagesh Adla, Thiyagu Rajakannan, Rajesh Valakkathala

pp. 131-134 · DOI: 10.4103/2230-973X.85961 · 2011

Chewing gum is an excellent drug delivery system for self medication as it is convenient, can be administered discreetly without water and offers the removal of ‘needle fear’ for the patients. As it releases insulin oral…

Jaydeep Patel, Kevin Garala, Biswajit Basu, Mihir Raval, Abhay Dharamsi

pp. 135-138 · DOI: 10.4103/2230-973X.85962 · 2011

In the present study we investigated the effect of polyamidoamine (PAMAM) dendrimers on the aqueous solubility of aceclofenac. The aqueous solubility of aceclofenac was measured in the presence of dendrimers in distilled…

Sanjula Baboota, Md Sarfaraz Alam, Shrestha Sharma, Jasjeet K Sahni, Anil Kumar, Javed Ali

pp. 139-147 · DOI: 10.4103/2230-973X.85963 · 2011

Introduction: Betamethasone dipropionate (BD) has anti-inflammatory, immunomodulatory, and antiproliferative activity. The aim of the current work was to test the hypothesis that the addition of corticosteroid such as BD…

Hemant H Gangurde, Mayur A Chordiya, S Tamizharasi, K Senthilkumaran, T Sivakumar

pp. 148-156 · DOI: 10.4103/2230-973X.85964 · 2011

Background: Oral sustained release gastroretentive dosage forms offer many advantages for drugs having absorption from upper gastrointestinal tract and improve the bioavailability of medications that are characterized by…

Kamlesh J Wadher, Rajendra B Kakde, Milind J Umekar

pp. 157-163 · DOI: 10.4103/2230-973X.85966 · 2011

The overall objective of the present work was to develop an oral sustained-release (SR) metformin tablet prepared by the direct compression method, using hydrophilic hydroxylpropylmethylcellulose (HPMC) and Guar gum poly…

Marina Koland, R Narayana Charyulu, Vijayanarayana K, Prabhakara Prabhu

pp. 164-171 · DOI: 10.4103/2230-973X.85967 · 2011

Buccal films of ondanstron hydrochloride were fabricated from mucoadhesive polymer, chitosan, and polyvinyl pyrrolidone (PVP K30) for the purpose of prolonging drug release and improving its bioavailability. All fabricat…

Dasharath M Patel, Rushiraj H Jani, Chhagan N Patel

pp. 172-181 · DOI: 10.4103/2230-973X.85969 · 2011

Introduction: A modified pulsincap dosage form of 5-fluorouracil was developed to target drug to colorectal carcinoma according to daily oscillations of rate-limiting metabolizing enzyme dihydropyrimidine dehydrogenase. …

R Indira Prasanna, P Anitha, C Madhusudhana Chetty

pp. 182-191 · DOI: 10.4103/2230-973X.85971 · 2011

Background: A novel aspiration in treatment of migraine, to provide greater therapeutic effect, overcome the side effects by complex therapeutic regimen and to improve patient compliance upon administering bucco-adhesive…

Karan Malik, Gurpreet Arora, Inderbir Singh, Sandeep Arora

pp. 192-198 · DOI: 10.4103/2230-973X.85973 · 2011

Aim: Orodispersible tablets also known as fast dissolving tablets disintegrate instantaneously within the mouth and thus can be consumed without water. The present study was aimed to formulate orodispersible tablets of n…