Volume 4, Issue 1

Aditya Ganeshpurkar, Ankit Ganeshpurkar, Vikas Pandey, Abhishek Agnihotri, Divya Bansal, Nazneen Dubey

pp. 1-4 · DOI: 10.4103/2230-973X.127733 · 2014

It seems to be a necessary need to develop an effective drug carrier system for targeted delivery of pharmaceuticals. Bacterial ghosts are emerging drug delivery platform that are capable of delivery of proteins, antigen…

Kushal Pal Singh, Gulshan Chhabra, Vijay Sharma, Kamla Pathak

pp. 5-14 · DOI: 10.4103/2230-973X.127734 · 2014

Aim: The aim of the present work was to explore the development of a dual-controlled release periodontal system of a potent broad spectrum fi rst-generation fl uoroquinolone, ciprofl oxacin, and the anti-infl ammatory en…

Suneela Pyreddy, Pandurangan Dinesh Kumar, Palanirajan Vijayaraj Kumar

pp. 15-18 · DOI: 10.4103/2230-973X.127735 · 2014

Aim: The preparation of novel PEGylated PAMAM (poly-amidoamine) dendrimers for delivery of anti-HIV drug Efavirenz is reported. Method and Materials: About 5.0 G PAMAM dendrimers are prepared by ethylene diamine core via…

K Rama Koteswara Rao, K Rajya Lakshmi

pp. 19-26 · DOI: 10.4103/2230-973X.127736 · 2014

Objective: The objective of the present work was to formulate and to characterize a fl oating drug delivery system for clopidogrel bisulphate to improve bioavailability and to minimize the side effects of the drug such a…

Shailesh T Prajapati, Manoj V Patel, Chhaganbhai N Patel

pp. 27-31 · DOI: 10.4103/2230-973X.127737 · 2014

Aim: Zolmitriptan is a 5-HT receptor agonist (1B/1D). It is used in the acute treatment of migraine having low bioavailability about 40% orally due to hepatic first pass metabolism. The purpose of the present research wa…

Keyur S Patel, Mandev B Patel

pp. 32-37 · DOI: 10.4103/2230-973X.127738 · 2014

Objectives: The objective of present study was to develop chitosan-based sustained release nicorandil microspheres to reduce the dosing frequency. Materials and Methods: The nicorandil-loaded chitosan microspheres were f…

Iizhar Ahmed Syed, P Niveditha, Ismail Ahmad

pp. 38-45 · DOI: 10.4103/2230-973X.127739 · 2014

Introduction: The polyelectrolyte Complexes (PECs) are based on ionic cross-linking. They have been employed to prepare a sustained release matrix tablets. These systems are based upon the fact that their structure can e…