International Journal of Pharmaceutical Investigation · Archive
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In this issue
Editorial
- Article
Javed Ali
pp. 199 · DOI: 10.4103/2230-973X.93002 · 2012
Topical eye drops are the most common dosage form for treating disorder related to the anterior segment of the eye. However, a large amount of drug delivered through the eye drops is lost through tear drainage and associ…
Review Article
Sagar Makwana, Biswajit Basu, Yogita Makasana, Abhay Dharamsi
pp. 200-206 · DOI: 10.4103/2230-973X.93004 · 2012
Parenteral administration of pharmaceutical products is one of the most popular methods used to produce quick onset of action and also 100% bioavailability. Main problem occurs with the parenteral drug delivery is lack o…
Original Research Article
Sanjay J Kshirsagar, Shrikant V Patil, Mangesh R Bhalekar
pp. 207-213 · DOI: 10.4103/2230-973X.93005 · 2012
Introduction: A pulsatile drug delivery system is characterized by a lag time that is an interval of no drug release followed by rapid drug release. The purpose of this work was to develop hollow calcium alginate beads f…
Shantanu V Lale, Monu Goyal, Arvind K Bansal
pp. 214-221 · DOI: 10.4103/2230-973X.93007 · 2012
Introduction: The purpose of the present study was to screen excipients such as amino acids and non-aqueous solvents for their stabilizing effect on catalase, a model protein, for lyophilization. The present study also i…
Santosh S Bhujbal, Sunita S Hadawale, Parag A Kulkarni, Jayant S Bidkar, Vidya A Thatte, Clarine A Providencia, Rupesh R Yeola
pp. 222-226 · DOI: 10.4103/2230-973X.93009 · 2012
Background and Aim: Momordica charantia Linn. is traditionally used as a medicine for diabetes. The present investigation was aimed to formulate and evaluate transdermal patchesof Momordica charantia Linn. Materials and …
Archana S Patil, Panchaxari M Dandagi, Vinayak S Masthiholimath, Anand P Gadad, Basavaraj K Najwade
pp. 227-223 · DOI: 10.4103/2230-973X.93010 · 2012
Background: Hypertension shows circadian rhythm that there is a rise in pressure from the time of waking or before (about 4 to 8 a.m.), in most people. Conventional drug delivery system of captopril is inappropriate for …
Rachna Prasad, Sneh Anand, Veena Koul
pp. 234-239 · DOI: 10.4103/2230-973X.93011 · 2012
Introduction: The effect of DC iontophoresis using low (0.2 mA/cm2) and high current density (0.5 mA/cm2) on transdermal permeation of methotrexate loaded into polyacrylamide hydrogel patch was investigated. Results: Flu…
Prabhakar Prabhu, Samip Shah, Shankar Gundad
pp. 240-246 · DOI: 10.4103/2230-973X.93008 · 2012
Aim and Background: Domperidone is a dopamine antagonist with antiemetic properties having a plasma half life of 7-9 h with 15% oral bioavailability. In the present work transdermal patches of domperidone were prepared w…
Dasharath M Patel, Mehul J Patel, Ankit N Patel, Chhagan N Patel
pp. 247-254 · DOI: 10.4103/2230-973X.93006 · 2012
Introduction: Present investigation describes an influence of ratio of Gelucire 43/01(hydrophobic) to hydroxypropyl methylcellulose K4M (HPMC K4M) (hydrophilic) and different fillers on release of famotidine from gastro-…
Letter to the Editor
- Article
Barkat Ali Khan
pp. 255 · DOI: 10.4103/2230-973X.93003 · 2012
I have read the editorial note titled 'Plagiarism: an editor's concern' by Dr Javed Ali and found it a bold and great decision by IJPI. Plagiarism is a serious contravention in modern age academic writing and research an…