International Journal of Pharmaceutical Investigation · Archive
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In this issue
Review Article
Amol N. Patil, Biswa Mohan Padhy, S. Krishna Prasanthi, Rachna Rohilla
pp. 1-6 · DOI: 10.4103/jphi.JPHI_103_17 · 2018
Medicine is a forever‑evolving science and commands continuous research. Pharmacologists and pharmacists contribute various amounts of medicine‑related information to physicians, while clinicians face challenges in evide…
Original Research Article
Arlene Stuart Villarroel, Madan Mohan Gupta, Lexley M. Pinto Pereira, Andanappa K. Gadad
pp. 7-13 · DOI: 10.4103/jphi.JPHI_3_18 · 2018
Objective: Metformin is a first‑line agent for the treatment of Type 2 diabetes. The taste of metformin hydrochloride drug powder is bitter and its formulation are orally used. The objective of this study was to make a c…
Jyothshna Devi Katamreddy, Prasanna Raju Yalavarthi, D. Subba Rao, SP. Surya Teja, Sowjanya Battu
pp. 14-23 · DOI: 10.4103/jphi.JPHI_9_18 · 2018
Objective: To optimize and characterize quetiapine (QP)‑loaded self‑nanoemulsified drug delivery systems (SNEDDS) by 3‑factorial 3‑level Box–Behnken design (BBD) to improve the dissolution. Methods: Amounts of olive oil …
Vuppalapati Lavakumar, Cherukuri Sowmya, Narayanan Venkateshan, Velayutham Ravichandiran, Kagithakara Vajravelu Leela, Narayanaswamy Harikrishanan, Jayaraman Anbu
pp. 24-32 · DOI: 10.4103/jphi.JPHI_101_17 · 2018
Background: Asthma is a chronic disease characterized by repeated attacks of breathlessness and wheezing, which occurs principally during night. This is due to circadian changes in ventilation and airway responsiveness. …
Mohd Alaraj, Bahaa Deen Al‑Trad, Samir Qiblawi, Audah Al Hazmi, Fahaad S. H. Alenazi, Ashfaque Hossain, Tolgahan Acar, Mohammad Almermesh, Mohammed Qumani Ahmed
pp. 33-37 · DOI: 10.4103/jphi.JPHI_95_17 · 2018
Aim: The main objectives of this work were to prove that subcutaneous injection of high doses of glucose can lead to occurrence of glycogen granules inside ultrastructurally changed mitochondria of mouse cerebral cortex …
Revathi Ramesh, N. Sarala, P. N. Venkatarathnamma
pp. 38-43 · DOI: 10.4103/jphi.JPHI_4_18 · 2018
Background: Hypertension is one of the most prevalent noncommunicable diseases. The Joint National Commission VIII guidelines recommend angiotensin receptor blockers (ARBs) as the first‑line drug and addition of hydrochl…
Peivand Bastani, Alireza Yusef, Parisa Dehghanian, Maryam Radin Manesh, Nasrin Shaarbafchi Zadeh, Fatemeh Khademian
pp. 44-49 · DOI: 10.4103/jphi.JPHI_86_17 · 2018
Background: Health care is a vitally sensitive area, in which the smallest medication error may lead to patient’s loss that cannot be compensated. In this area, information technology is a useful tool for practical impro…
Letter to the Editor
- Article
Jasjeet Kaur Narang, Ramandeep Singh Narang, Balwinder Singh, Sukhdeep S. Kahlon, Jiji George, Anmol Dogra
pp. 50-52 · DOI: 10.4103/jphi.JPHI_14_18 · 2018
Dear Sir, Candida, a type of fungus, can cause infections, which can be either local or systemic. The human body hosts small amounts of this fungus under normal conditions. However, problems arise when it begins to multi…