International Journal of Pharmaceutical Investigation · Archive
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In this issue
Review Article
Avinash Y Kaushik, Ajay K Tiwari, Ajay Gaur
pp. 1-12 · DOI: 10.4103/2230-973X.147219 · 2014
Since decade or two, the development of floating drug delivery systems becomes a significant and novel tool as having low density than gastric content. There are various advanced polymers including chitosan, eudragit, et…
Upendra Nagaich, Divya Sadhna
pp. 13-19 · DOI: 10.4103/2230-973X.147222 · 2014
There has been an increasing trend in the number of prescribed and over-the-counter drug recall over the last few years. The recall is usually due to company’s discovery, customer’s complaint or Food and Drug Administrat…
Original Research Article
Hirva A Shah, Rakesh P Patel
pp. 20-27 · DOI: 10.4103/2230-973X.147229 · 2014
Objective: The main objective of this study is to formulate polymeric nanoparticles (NPs) loaded with zaltoprofen, an NSAID drug. The optimization, in terms of polymer concentration, stabilizer concentration and pH of th…
Panuganti Venkataharsha, Ellutla Maheshwara, Prasanna Raju Y, Vayalpati Ashok Reddy, Bandugalla Sanjeev Rayadu, Basappa Karisetty
pp. 28-34 · DOI: 10.4103/2230-973X.147230 · 2014
Introduction: The present aim of this study was to formulate naproxen and nimesulide liposomal formulation for incorporation in Aloe vera transemulgel and to carry out in vitro and in vivo evaluation of the formulation.M…
Rajesh Ramesh Hosadurga, Sudarshan Narayan Rao, Rejeesh Edavanputhalath, Jobin Jose, Narayana Charyulu Rompicharla, Moidin Shakil, Shashidhara Raju
pp. 35-42 · DOI: 10.4103/2230-973X.147231 · 2014
Introduction: One of the options for the treatment of periodontitis is local drug delivery systems (LDD). Tulsi (Ocimum sanctum), a traditional herb, has many uses in medicine. It could be a suitable agent as LDD for the…
Rajyalakshmi Kadiyam, Y. Indira Muzib
pp. 43-49 · DOI: 10.4103/2230-973X.147232 · 2014
Objective: The objective of present work is to develop and evaluate a matrix system for Chronotherapeutic delivery of centrally acting of opioid analgesic (tramadol HCl) to treat nocturnal symptoms of arthritis using alm…
Priya Patel, Paresh Patel
pp. 50-56 · DOI: 10.4103/2230-973X.147233 · 2014
Objective: The vagina has been studied as a favorable site for the local and systemic delivery of drugs, for female associated conditions. Vaginal preparations, although generally perceived as safer most still associated…
Arti Mohan, Rohit Gundamaraju
pp. 57-64 · DOI: 10.4103/2230-973X.147235 · 2014
Aim: Investigation of in vitro/in vivo behavior of fast-dissolving tablets containing solid dispersions (SDs) of lamotrigine (LM) was the aim and focus of the present research work. Material and Methods: The effect of va…