International Journal of Pharmaceutical Investigation · Archive
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In this issue
Review Article
Rajeshri Dineshbhai Patel, Yamini Anilbhai Bhalani, Dhruti Sanjaybhai Sudani Sudani, Lipsa Ashvinbai Vachhani
pp. 1-6 · DOI: 10.5530/ijpi.2022.1.1 · 2022
Tamoxifen (TAM), a non-steroidal antiestrogen, has revolutionized female breast cancer treatment. The mechanism involves is to compete with 17β-estradiol (E2) at the receptor site and blocking the promotional role of E2 …
Original Article
T. H. Mohamed Ahadu Shareef, Mohamed Divan Masood
pp. 7-14 · DOI: 10.5530/ijpi.2022.1.2 · 2022
Background: Glycyrrhiza glabra,Terminalia chebulaandHamdard joshandais used as a traditional home medicine in developing countries that is easily available for a lesser cost with no side effects. These medicine decoction…
Swami Pooja Ganpat, Singhavi Dilesh Jagdish, Ganjiwale Rajendra Onkarappa
pp. 15-19 · DOI: 10.5530/ijpi.2022.1.3 · 2022
Background: Aegle marmelos is an important ethnomedicinal plant that is found commonly in India and other Asian countries. The peel of the fruit is hard and is often discarded as waste. However, a few studies have shown …
Imène Becheker, Ali Becheker, Mohamed Akram Melakhessou, Salah Eddine Marref, Hajira Berredjem
pp. 20-27 · DOI: 10.5530/ijpi.2022.1.4 · 2022
Background: The Pharmaceutical companies are very interested in the discovery of new natural bioactive molecules with an impoortant effect and less toxicity, in order to replace old drugs, especially antibiotics which ha…
Kiran Kharat, Sonal Jawale, Amol R Kharat, Preetha Achary, Vinod R Ragade
pp. 28-32 · DOI: 10.5530/ijpi.2022.1.5 · 2022
Background: Moringa oleifera Lam. (Family: Moringaceae), commonly known as ‘drumstick tree’ is beneficial to obtain sustenance as a food source and applied as a traditional medicine. The therapeutic potential ofMoringa o…
Murugan Sellappan, Kumar Giriappa Venkatesh
pp. 33-38 · DOI: 10.5530/ijpi.2022.1.6 · 2022
Background: Plants are an important source of medicine. Most of the plants are studied for their therapeutic values and to treat various diseases. Hygrophila schulli is one of the important medicinal plants belonging to …
Ankita Awasthi, Bhaskar Kumar Gupta, Papiya Bigoniya
pp. 39-45 · DOI: 10.5530/ijpi.2022.1.7 · 2022
Background: The present study was investigated about the anti-obesity effect of dill seed cake on rats fed with high fructose diet. Materials and Methods:45 days experimental study of high fructose diet feeding induced o…
Yash Desai, Micky Patel, Ravikiran Panakanti
pp. 46-50 · DOI: 10.5530/ijpi.2022.1.8 · 2022
Background: Diabetes mellitus is a fast spreading metabolic disease in both developed and developing countries owing to genetic predisposition, lifestyle and or environmental conditions. Recombinant insulin used for mana…
Mukkala Prasada Reddy, Obireddy Sreekanth Reddy, Marata Chinna Subbarao Subha
pp. 51-55 · DOI: 10.5530/ijpi.2022.1.9 · 2022
Background: The present work is focused on developing a simple stability indicating method for the estimation of the assay of benzyl alcohol and glycopyrrolate in glycopyrrolate injection using reverse high performance l…
Ravisinh Vikramsinh Solanki, Ravi Bharatkumar Patel, Rajeshkumar Kanubhai Patel, Riya Alpeshkumar Sheth
pp. 56-61 · DOI: 10.5530/ijpi.2022.1.10 · 2022
Objectives: A precise, accurate and selective stability-indicating reverse phase high performance liquid chromatographic assay method has been developed for the simultaneous quantitative determination of Tolperisone hydr…
Mohamed Shiffa, M Aslam, MH Kazmi, Syed Mansoor Ali, Nazeem Fahamiya, Mohammad Mahfuzul Haque
pp. 62-65 · DOI: 10.5530/ijpi.2022.1.11 · 2022
Background: Cinnamomum zeylanicum (Darchini), Alpinia galanga (Khulanjan), and Withania somnifera (Asgand) have been used in joint diseases by Unani scholars since long. The combination of these ingredients may be more e…
Prafulla R Tathe, Rakeshkumar Jat, Amjadkhan Pathan, Kailas Biyani
pp. 66-69 · DOI: 10.5530/ijpi.2022.1.12 · 2022
Background: The aim of present study was to find protective effect of α-asarone in cisplatin-induced hepatotoxicity in experimental rats. Materials and Methods: The rats were divided into 5 groups at randomly. Cisplatin …
Dollyca Ningombam, Toijam Sanjeev Lyngdoh, Maibam Damayanti Devi
pp. 70-74 · DOI: 10.5530/ijpi.2022.1.13 · 2022
Background: From time immemorial medicinal plants are used in treating urolithiasis in ayurvedic system and other forms of traditional health practitioners. In Manipur, local traditional health practitioners used Cissus …
Nur Farzana Jaslina, Nur Hana Faujan, Rosfarizan Mohamad, Siti Efliza Ashari
pp. 75-81 · DOI: 10.5530/ijpi.2022.1.14 · 2022
Background: Kojic monooleate (KMO) contains tyrosinase inhibitor and exhibits strong antioxidant activity makes it a good candidate to be incorporated into a formulation for topical application. A peel-off was chosen to …
Rahul Padalkar, Ashwini Madgulkar, Rohit Kharade
pp. 82-86 · DOI: 10.5530/ijpi.2022.1.15 · 2022
Background: This work is based on the development of a wound healing dressing system for diabetic wounds using curcumin and syringic acid. A diabetic wound differs from a normal wound in respect to many pathophysiologica…
C Sowmya, V Lava Kumar, Bishnu Adhikari
pp. 87-92 · DOI: 10.5530/ijpi.2022.1.16 · 2022
Background: Xanthan gum (XG) is a natural polymer with numerous uses. But its poor tableting and release charact1eristics reduce its usage as a tablet matrix former. Hence, the aim of the study is to improve the quality …
Singh Jagpal, Mahendra Singh
pp. 93-96 · DOI: 10.5530/ijpi.2022.1.17 · 2022
Objective: The objective of this paper was to fabricate and increase the effectiveness of the formulation of Solid lipid nanoparticle (SLN) on improving the oral bioavailability of Famotidine. Methods: In this study, ult…
Mallikarjun Kappi, Murthy Chavali, Chaman Sab M, KK Mueen Ahmed
pp. 97-103 · DOI: 10.5530/ijpi.2022.1.18 · 2022
Aim: The present study aims to trace out the comparative mapping of World and Indian Nanocellulose research output. Methodology: The Science Citation Index (SCI) of Web of Science (WoS) core collection was used data extr…
Case Report
- Article
Sahithi Maroju, K Krishna Sumanth
pp. 104-106 · DOI: 10.5530/ijpi.2022.1.19 · 2022
An 18-year female presented with an alleged history of the conception of liquid paraquet of an unknown quantity on 3rd August 2021. On examination, the patient was unconscious and disoriented. She was further diagnosed w…
Retraction Notice
- Article
pp. 107 · 2022
The article titled “Ameliorative Effect of Falcaria vulgaris on Nicotine-induced Injury on the Hippocampus Dentate Gyrus Region of Rats” published in 2019 (Vol. 9(9), pp. 200-204) has been retracted from the journal afte…