International Journal of Pharmaceutical Investigation · Archive
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In this issue
Editorial
- Article
Jasjeet Kaur Narang
pp. 107-108 · DOI: 10.4103/2230-973X.138337 · 2014
Administration of lipophilic drugs by oral route is a challenging task due to multiple factors which include poor solubilization of a drug in the gastrointestinal tract, P-glycoprotein efflux, significant first pass elim…
Review Article
Sukhvinder Singh Oberoi, Avneet Oberoi
pp. 109-111 · DOI: 10.4103/2230-973X.138338 · 2014
Although the government pays for approximately 20% of drugs used in India, private out-of-pocket expenditure in India on health-care is one of the highest in the world. Preparing pharmacoeconomics guidelines will be an i…
Original Research Article
Akhilesh Dubey, Prabhakara Prabhu
pp. 112-118 · DOI: 10.4103/2230-973X.138340 · 2014
Background: Stimuli-sensitive hydrogels are hydrophilic, three-dimensional, polymeric network structure capable of imbibing large amounts of water or biological fl uids on stimulation, such as pH, temperature, and ionic …
Mohd Yusuf, Vijay Sharma, Kamla Pathak
pp. 119-130 · DOI: 10.4103/2230-973X.138342 · 2014
Aim: The research traces development of nanovesicles to attain enhanced transdermal delivery of felodipine and also investigates parameters for optimization of variable membrane compositions containing soya- and egg leci…
Kiran Thadkala, Prema Kumari Nanam, Bathini Rambabu, Chinta Sailu, Jithan Aukunuru
pp. 131-137 · DOI: 10.4103/2230-973X.138344 · 2014
Objectives: The objective of this study was to prepare and investigate better and stable amorphous ezetimibe nanosuspensions for oral bioavailability enhancement. Materials and Methods: Nanosuspensions of ezetimibe were …
Radha A. Deshmukh, Anjana S. Bagewadi
pp. 138-141 · DOI: 10.4103/2230-973X.138346 · 2014
Introduction: Recurrent aphthous stomatitis (RAS) is an unfortunately most common disease occurring in oral cavity. Although the lesion is usually self-limited, its painful presentation, high frequency of occurrence, and…
Josephine Leno Jenita, Vijaya Chocalingam, Barnabas Wilson
pp. 142-148 · DOI: 10.4103/2230-973X.138348 · 2014
Purpose of the study:The antiretroviral therapy (ART) has dramatically improved human immunodefi ciency virus (HIV)/ acquired immunodefi ciency syndrome (AIDS) treatment, prevention and also has been found to increase th…