International Journal of Pharmaceutical Investigation · Archive
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In this issue
Review Article
Mohd Urooj, Gulam Mohammed Husain, Mohammad Ahmed Khan, Munawwar Husain Kazmi
pp. 41-46 · DOI: 10.4103/jphi.JPHI_31_17 · 2017
The recent amendments notified by the Government of India, for conducting clinical trial, is greatly appreciable as promoting safety and well‑being of human subjects. These rules clearly state that medical management of …
Nitin B Charbe, Paul A McCarron, Majella E Lane, Murtaza M Tambuwala
pp. 47-59 · DOI: 10.4103/jphi.JPHI_32_17 · 2017
Orally administered solid dosage forms currently dominate over all other dosage forms and routes of administrations. However, human gastrointestinal tract (GIT) poses a number of obstacles to delivery of the drugs to the…
Original Research Article
Seyed Mojtaba Mosavian, Azam Rezvani‑Rad
pp. 60-69 · DOI: 10.4103/jphi.JPHI_4_17 · 2017
Objective: The purpose of conducting this research was evaluation of the frequency of extended‑spectrum beta‑lactamases (ESBLs) in separated Enterobacteriaceae isolates from clinical samples in Khorramabad city and deter…
Fatima Zehra, Atta Abbas Naqvi, Sumbul Tasneem, Rizwan Ahmad, Niyaz Ahmad, Adnan Zia Shamsi, Naqiya Ali Asghar, Ghufran Ullah Khan
pp. 70-76 · DOI: 10.4103/jphi.JPHI_15_17 · 2017
Introduction: Pakistan spends 0.7% of its gross domestic product on health. The public sector health‑care system provides services to 22% of population thus paving the way for a dominant private sector. Patients in Pakis…
Sahar Karami, Mohammad Roayaei, Elnaz Zahedi, Mahmoud Bahmani, Leila Mahmoodnia, Hosna Hamzavi, Mahmoud Rafieian-Kopaei
pp. 77-81 · DOI: 10.4103/jphi.JPHI_9_17 · 2017
Objective: The Lactobacillusis a genus of lactic acid bacteria which are regularly rod‑shaped, nonspore, Gram‑positive, heterogeneous, and are found in a wide range of inhabitants such as dairy products, plants, and gast…
Gholam-Reza Talei, Mohsen Mohammadi, Mahmoud Bahmani, Mahmoud Rafieian Kopaei
pp. 82-87 · DOI: 10.4103/jphi.JPHI_12_17 · 2017
Background: Infectious diseases have always been an important health issue in human communities. In the recent years, much research has been conducted on antimicrobial effects of nature‑based compounds because of increas…
Manisha Singh, Anjana Bagewadi
pp. 88-93 · DOI: 10.4103/jphi.JPHI_19_17 · 2017
Aim: The aim of the study is to assess the efficacy of Calendula officinalis gel as cost‑effective treatment modality in comparison to lycopene gel in the treatment of leukoplakia. Materials and Methods: The study compri…
P Naveen, HB Lingaraju, Anitha A, K Shyam Prasad
pp. 94-100 · DOI: 10.4103/jphi.JPHI_33_17 · 2017
Objective: The present study was investigated to provide a documentary evidence for the determination of rutin, isoquercetin, and quercetin flavonoids from the flora of Nelumbo nuciferaby reversed‑phase high‑performance …
Swaminathan Rajendran, K. Sathesh Kumar, S Ramesh, Suresh Ranga Rao
pp. 101-106 · DOI: 10.4103/jphi.JPHI_26_17 · 2017
Objective: The aim of this in vitro study was to formulate an in situ thermoreversible injectable gel with poloxamer (PM) and methylcellulose (MC) to deliver simvastatin (SMV) in a controlled manner. Subjects and Methods…
Case Report
- Article
Raghavendra Adaki, Sarvesh Raikar, Kamal Shigli, Sivaranjani Gali
pp. 107-110 · DOI: 10.4103/jphi.JPHI_17_17 · 2017
Objective: This article aims to highlight the rehabilitation of a geriatric patient with an orofacial cheek defect by an extraoral silicone prosthesis. Methodology: Structured extra‑ and intra‑oral examination of tissues…