Volumes & Issues

Original Research Article

1. Usnic acid‑loaded bioinspired heparin modified‑cellulose acetate phthalate nanoparticle(s) as an efficient carrier for site‑specific delivery in lung cancer cells

   Ashish Garg, Nitendra K. Sahu, Awesh Kumar Yadav

   pp. 53-62 · DOI: 10.4103/jphi.JPHI_5_18 · 2018

   Introduction: The main goal of the current study was to assess the cytotoxic influence of usnic acid (UA) after enclosement in heparin modified‑cellulose acetate phthalate (HEC) nanoparticles(NPs) when targeted to lung c…

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2. In vivo evaluation of the aromatase inhibition by 4‑((1H‑imidazol‑1‑yl) methyl)‑2‑(4‑fluorophenyl)‑ 8‑phenylquinoline

   Navid Sedighi, Razieh Ghodsi, Gholamreza Karimi, Hossein Kamali, Farzin Hadizadeh

   pp. 63-68 · DOI: 10.4103/jphi.JPHI_17_18 · 2018

   Objective: Some of aromatase inhibitors(AIs) are Food and Drug Administration‑approved agents which are used as first‑line therapy in the treatment of endocrine‑responsive breast cancer. In this study, we aimed to develo…

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3. Distinguishing adverse drug reactions, the noxious effects of medicines at a tertiary care hospital

   Siavash Shahbazi Nia, Shadan Modaresahmadi, Armin Eisa Zaei

   pp. 69-73 · DOI: 10.4103/jphi.JPHI_24_18 · 2018

   Introduction: Adverse drug reactions (ADRs) are unavoidable and are considered as the fourth‑to‑sixth leading causes of death. It makes it essential to detect and monitor the ADRs. Hence, this study was aimed to identify…

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4. Mesalamine-loaded mucoadhesive microsphere for colon drug delivery system: Effect of process variables and in vitro characterization

   Anup Patil, Pravin Pawar, Varsha Gharge, Ujjwala Doltade, Rajendra Doijad

   pp. 74-82 · DOI: 10.4103/jphi.JPHI_22_18 · 2018

   Objective: The main objective of this study is to formulate mucoadhesive microspheres for colon drug delivery with sodium alginate (ALG) core enriched with drug.Methods: The core microspheres of ALG were prepared by modi…

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5. Development and investigation of novel solid self‑nanoemulsifying system loaded with hydrochlorothiazide for the treatment of hypertension

   Akhilesh Dubey, Amitha Shetty, G. S. Ravi, Manan Christian Kiritkumar, Prabhakara Prabhu, Srinivas Hebbar, Sally A. El‑Zahaby

   pp. 83-91 · DOI: 10.4103/jphi.JPHI_29_18 · 2018

   Objective: The present study was aimed at formulating and evaluating a novel solid self‑nano emulsifying drug delivery system (SNEDDS) to increase the solubility and bioavailability of hydrochlorothiazide (HCZ). Enhancin…

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6. An evaluation of classification algorithms for prediction of drug interactions: Identification of the best algorithm

   Rita Rezaee, Reza Akbari, Milad Nasiri, Farzaneh Foroughinia, Nasrin Shokrpour

   pp. 92-99 · DOI: 10.4103/jphi.JPHI_19_18 · 2018

   Introduction: One of the main causes of medical errors is drug interaction which occurs when a drug decreases or increases the effect of another drug. Drug interactions occur as a result of changes in pharmacodynamics, p…

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7. Evaluation of efficacy and safety of Ayucid capsule in subjects suffering from chronic symptomatic gastroesophageal reflux disease

   Sanjay M. Tamoli, Shishir P. Pande, Shailesh V. Deshpande, Narendra B. Mundhe, Mandar V. Doiphode, Ganesh S. Kolhe, Sachin A. Upasani

   pp. 100-105 · DOI: 10.4103/jphi.JPHI_35_18 · 2018

   Objectives: The objective of the study was to assess the efficacy and safety of Ayucid capsule and Omeprazole 20 mg in patients suffering from chronic symptomatic gastroesophageal reflux disease (GERD). Materials and Met…

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8. Digital health research: A scientometric assessment of global publications output during 2007–2016

   B. M. Gupta, S. M. Dhawan, K. K. Mueen Ahmed

   pp. 106-114 · DOI: 10.4103/jphi.JPHI_31_18 · 2018

   Aim and Scope: To study the scientometric assessment of global publications on Digital Health Research. Methods: The paper examines digital health research covering 6981 global publications sourced from Scopus database d…

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