International Journal of Pharmaceutical Investigation · Archive
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In this issue
Editorial
- Article
Javed Ali
pp. 61 · DOI: 10.4103/2230-973X.82382 · 2011
Nanotechnology is now a part of our everyday life with or without our knowledge. Then, why can pharmaceutics not conceive this technology for its betterment? Yes, the same has been done for many years in the past in phar…
Guest Editorial
- Article
Kamla Pathak
pp. 62-63 · DOI: 10.4103/2230-973X.82383 · 2011
Nasal drug administration has frequently been proposed as the most feasible alternative to parenteral injections. This is due to the high permeability of the nasal epithelium, allowing a higher molecular mass cut-off at …
Review Article
CH Saroja, PK Lakshmi, Shyamala Bhaskaran
pp. 64-74 · DOI: 10.4103/2230-973X.82384 · 2011
Vaccines are the preparations given to patients to evoke immune responses leading to the production of antibodies (humoral) or cell-mediated responses that will combat infectious agents or noninfectious conditions such a…
Invited Article
Bhupinder Singh, Rahul Bhatowa, Chandra Bhushan Tripathi, Rishi Kapil
pp. 75-87 · DOI: 10.4103/2230-973X.82395 · 2011
Of late, micro and nanoparticluate drug delivery systems have been gaining immense importance primarily attributed to their improved drug release controlling and targeting efficiencies. Also, the small particle size and …
Original Research Article
Sung-Wook Choi, Hye Min Lee, Tae-Joon Park, Jung-Hyun Kim
pp. 88-92 · DOI: 10.4103/2230-973X.82402 · 2011
This paper describes the synthesis of thermosensitive surfactants by polymerizing N-isopropylacrylamide (NIPAAm) into the Pluronic F68 surfactant and their application for a controlled drug release. Poly(NIPAAm)-Pluronic…
Anita Saxena, Abu Tahir, Mandeep Kaloti, Javed Ali, Himadri B Bohidar
pp. 93-98 · DOI: 10.4103/2230-973X.82407 · 2011
The study was designed for the development of salbutamol-modified release tablet using various polymer composition of agar, gelatin A and gelatin B. The purpose is to observe the role of polymer composition on the modifi…
Prabhakara Prabhu, Ravi Malli, Marina Koland, K Vijaynarayana, Ullas D’Souza, Harish NM, CS Shastry, RN Charyulu
pp. 99-104 · DOI: 10.4103/2230-973X.82417 · 2011
Introduction: Levocetirizine dihydrochloride is an orally active, third-generation non-sedative antihistamine used in the symptomatic relief of seasonal and perennial allergic rhinitis. The present work aimed at preparin…
Formulation development and in vitro evaluation of gastroretentive hollow microspheres of famotidine
Mayur A Chordiya, Hemant H Gangurde, Senthilkumaran K, Lokesh P Kothari
pp. 105-111 · DOI: 10.4103/2230-973X.82423 · 2011
Background: The main aim of this study was to develop a gastroretentive, multiple-unit floating drug delivery system for a drug which is poorly absorbed from the lower gastrointestinal tract. Such a dosage form may provi…
Jaydeep Patel, Garala Kevin, Anjali Patel, Mihir Raval, Navin Sheth
pp. 112-118 · DOI: 10.4103/2230-973X.82431 · 2011
Background and Aim: Telmisartan (TEL) is an angiotensin II receptor blocker (ARB) antihypertensive agent. The aim of the present investigation was to develop a self-nanoemulsifying drug delivery system (SNEDDS) to enhanc…
AV Jithan, K Madhavi, Madhavi M, Prabhakar K
pp. 119-125 · DOI: 10.4103/2230-973X.82432 · 2011
Introduction: For the real-time clinical utilization of curcumin (an ayurvedic natural product) to treat breast cancer, its dissolution, rate limited solubility, poor tissue absorption, and extensive in vivo metabolism t…
Upcoming Events
- Article
pp. 126-128 · 2011
Nasal and Buccal Drug Delivery - Annual International Conference Date: April 04-05, 2011, Place: London, UK Details: The participants can gain an update on the very latest scientific developments and technology advances …