International Journal of Pharmaceutical Investigation · Archive
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In this issue
1–20 of 25Review Article
Subashini Rajaram, Senthil Rajan Dharmalingam, Vignesh Natarajan, Kaveena Ravi, Nivetha Shanmugam, Subbhashini Maruthamuthu Somasundaram
pp. 108-112 · DOI: 10.5530/ijpi.2022.2.20 · 2022
In recent years pharmaceutical companies are directing towards designing new pharmaceutical dosage forms of existing medications. Recent breakthroughs have been the inclusion of pharmaco-therapeutic characteristics of dr…
Bhatia Hemant, Kumar Dinesh, Ahuja Dharmendra
pp. 113-116 · DOI: 10.5530/ijpi.2022.2.21 · 2022
Plumbago indica L. is a remedial herb species in the genus of Plumbago described by Linnaeus of the species of Plantarum, extensively in the hot and humid areas to use in the conventional structure of herbs. The distinct…
Purushotham KN, TY Pasha, B Ramesh
pp. 117-122 · DOI: 10.5530/ijpi.2022.2.22 · 2022
Numerous bioactive heterocyclic products containing carbazole nucleus showed pharmacological and biological significance. Carbazole have been found in several of significant drug like fragments which provided a precious …
Sujata Sharma, Shweta Vashist, Avneet Kaur Lamba, Saahil Arora, Sucheta s
pp. 123-128 · DOI: 10.5530/ijpi.2022.2.23 · 2022
Skin break out and eruptions is a typical incendiary issue among people of all age groups, but most common in adolescents. Skin break out development is reliant upon mechanisms, including follicular hyper keratinization,…
Pranay Wal, Ankita Wal, Himangi Vig, Ashish Srivastava, Avnesh Kumar
pp. 129-135 · DOI: 10.5530/ijpi.2022.2.24 · 2022
A spike protein is a protein that builds a huge spike that ejects from an enveloped virus’s membrane. The spike protein is the only virus membrane protein that enables the virus to penetrate through the cell. Spike Prote…
Payel Mukherjee, Arindam Chakraborty, Manas Chakraborty, Goutam Mukhopadhyay
pp. 136-140 · DOI: 10.5530/ijpi.2022.2.25 · 2022
These days, carbon dots (CDs) are the rising stars of nanomaterials. Carbon dots (CDs) are small carbon nanoparticles with the same type of surface passivation (less than 10 nm in size). Researchers found C-dots by accid…
Alaa Hamed Habib
pp. 141-144 · DOI: 10.5530/ijpi.2022.2.26 · 2022
The word “tumor” is a Greek term that refers to a swelling or a lump. In modern medical terms, a tumor is usually an abnormal mass of cells and tissues which grows due to the abnormal division of cells. The unnatural div…
Majidah Aljadani
pp. 145-150 · DOI: 10.5530/ijpi.2022.2.27 · 2022
Breast cancer is the most prevalent cancer among women and is considered a societal burden. The current treatment strategies are limited to chemotherapy, radiotherapy, and surgery, governed by the tumor’s size, stage, an…
Najat Binothman
pp. 151-159 · DOI: 10.5530/ijpi.2022.2.28 · 2022
Despite exponential advancements in medical research, various types of cancer are increasing day by day and becoming a leading cause of mortality worldwide. The worldwide cancer burden has increased to 19.3 million new c…
Original Article
Falguni Saraswat, Mukeshkumar Nariya, Vinay J Shukla
pp. 160-164 · DOI: 10.5530/ijpi.2022.2.29 · 2022
Background: Celosia argentea Linn. (C. argentea) commonly known as Cock’s Comb. It’s a leading leafy vegetable used for treatment of anti inflammatory, antioxidant and possessing immunostimulating activities. This specie…
Bashir Ahmad Sheikh, Basharat Ahmad Bhat, Rakeeb Ahmad Mir, Zahoor Ahmad, Manzoor Ahmad Mir
pp. 165-172 · DOI: 10.5530/ijpi.2022.2.30 · 2022
Background: Due to the fact that pulmonary tuberculosis (PTB) is a highly infectious disease characterized by high herd susceptibility and hard to be treated. Cytokines have a crucial role in eliciting protective and pat…
Kailas Rangnath Labhade
pp. 173-177 · DOI: 10.5530/ijpi.2022.2.31 · 2022
Objectives: The present study was focused on environment friendly synthesis of cynopyridone compounds. New improved, three component, one-pot, solvent-free method was successfully developed for the synthesis of 3,4 -diar…
Poonam Karekar, Suresh Killedar
pp. 178-182 · DOI: 10.5530/ijpi.2022.2.32 · 2022
Background: The purpose of this study was to assess the antiasthmatic activity of Euphorbia hirta extract and Euphorbia hirta phytosomes in an in vitro anti-asthmatic model. Materials and Methods: The phytosomes were tes…
Srivani Mallepelli, Sreelatha Kamera, Achaiah Garlapati
pp. 183-190 · DOI: 10.5530/ijpi.2022.2.33 · 2022
Objectives: To develop a simple, rapid, reliable and precise RP-UPLC method for the simultaneous estimation of lamivudine, didanosine and efavirenz in bulk and its tablet dosage forms. Materials and Methods: The chromato…
Sandip Ashok Murtale, Prakash Goudanavar, Ankit Acharya, Jayatheertha Lokapur
pp. 191-198 · DOI: 10.5530/ijpi.2022.2.34 · 2022
Background: In the medical and pharmaceutical fields, man has made successful use of natural origin things for millennia. Natural medications and excipients have piqued the interest of the entire globe today. Obtained fr…
Vivek Verma, T S Easwari
pp. 199-204 · DOI: 10.5530/ijpi.2022.2.35 · 2022
Objectives: This research’s primary goals are Leflunomide (LFD) nanoemulgel formulation and characterization for topical administration. Materials and Methods: A pseudo ternary phase diagram was created utilizing castor …
Sachin Manik Jadhav, Sagar Kumar Mishra
pp. 205-210 · DOI: 10.5530/ijpi.2022.2.36 · 2022
Background: The traditional oral formulation for Alzheimer’s disease treatment has the drawbacks of first-pass metabolism, plasma protein binding, and poor blood-brain barrier penetration. This study was conducted to est…
Koliyote Sheeja, Shaji Jessy
pp. 211-215 · DOI: 10.5530/ijpi.2022.2.37 · 2022
Introduction: Synthesis of gold nanoparticles (GNPs) from various biological systems have been reported, but amongst them biosynthesis of GNPs from plants is considered as the most suitable method. The aim of this study …
Sudha Bansal, Dinesh Dhingra
pp. 216-222 · DOI: 10.5530/ijpi.2022.2.38 · 2022
Background: Gentisic acid has been reported to show neuroprotective effect. But its effect on depression is not available in the literature. So we evaluated the effect of this compound on depressive behavior in unstresse…
Raghunandan Hota, Bikash Kumar Nanda, Biswaranjan Behera, Chandan Das, Ashutosh Meher
pp. 223-227 · DOI: 10.5530/ijpi.2022.2.39 · 2022
Background: Capparis zeylanica (Capparaceae), a climbing shrub find its distribution throughout the different parts of India. Traditionally, it is used in the treatment of snake bite, small pox, stomach ulcers, piles, ch…