International Journal of Pharmaceutical Investigation · Archive
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In this issue
Review Article
Rima B. Shah, Manhar Patel, David M. Maahs, Viral N. Shah
pp. 1-9 · DOI: 10.4103/2230-973X.176456 · 2016
Many patients with advanced type 2 diabetes mellitus (T2DM) and all patients with T1DM require insulin to keep blood glucose levels in the target range. The most common route of insulin administration is subcutaneous ins…
Original Research Article
Ebere I Okoye, Anthony O Onyekweli
pp. 10-22 · DOI: 10.4103/2230-973X.176461 · 2016
Aim: The aim was to develop a novel excipient from Pleurotus tuber-regium (PT)-cornstarch (CS) mixture and evaluate its multifunctional characteristics in tablet formulation. Materials and Methods: Composites were genera…
Garima Thakur, Amrinder Singh, Inderbir Singh
pp. 23-31 · DOI: 10.4103/2230-973X.176468 · 2016
Composite transdermal films of chitosan (CS)/montmorillonite K 10 (MMT) clay were prepared for the delivery of curcumin. CS/MMT films were evaluated for various physicochemical parameters. The films were characterized by…
Franklin C. Kenechukwu, Mumuni A. Momoh, Emmanuel C. Umeyor, Emmanuel M. Uronnachi, Anthony A. Attama
pp. 32-38 · DOI: 10.4103/2230-973X.176473 · 2016
Background: The aim of this study was to formulate solidified reverse micellar solution (SRMS)-based solid lipid microparticles (SLMs) using homolipids from tallow fat (Bos indicus) and evaluate its potential for enhance…
Neha Sureshrao Raut, Swapnil Jamaiwar, Milind Janrao Umekar, Nandkishor Ramdas Kotagale
pp. 39-46 · DOI: 10.4103/2230-973X.176474 · 2016
Introduction: This study focused on the potential effects of compression forces experienced during lactose (InhaLac 70, 120, and 230) storage and transport on the flowability and aerosol performance in dry powder inhaler…
Renuka Mishra, Priyanka Joshi, Tejal Mehta
pp. 47-55 · DOI: 10.4103/2230-973X.176487 · 2016
Objective: The objective of the present investigation was formulation, optimization and characterization of mucoadhesive film of clotrimazole (CT) which is patient-convenient and provides an effective alternative for the…
Dinesh Kumar Pandurangan, Prathima Bodagala, Vijayaraj Kumar Palanirajan, Saravanan Govindaraj
pp. 56-62 · DOI: 10.4103/2230-973X.176488 · 2016
In the present investigation, solid lipid nanoparticles (SLNs)-loaded in situ gel with voriconazole drug was formulated. Further, the formulation was characterized for pH, gelling capacity, entrapment efficiency, in vitr…
Shamsuddin s, Mohammad Fazil, Shahid Husain Ansari, Javed Ali
pp. 63-68 · DOI: 10.4103/2230-973X.176490 · 2016
Introduction: Solubility and dissolution of a poor water-soluble drug are the two major barriers for formulation scientists in development of drug delivery. Many of the potent drugs do not show the therapeutic effects du…