International Journal of Pharmaceutical Investigation · Archive
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In this issue
Review Article
Arti Swami, Shalaka Abhyankar, Mugdha Kulkarni, Harshal Mundada
pp. 248-253 · DOI: 10.5530/ijpi.2021.3.44 · 2021
The rate and extent of absorption of a drug from its dosage form is referred to as bioavailability. While bioequivalence between two drug products is attained if their extent and rate of absorption do not relatively diff…
Rahul Kumar Sharma, Harsimran Singh, Devinder Kaur, Yogesh Kumar
pp. 254-259 · DOI: 10.5530/ijpi.2021.3.45 · 2021
Memory and cognitive functions are some of the most important and complex functions performed by the human brain. Any disorders which affect our memory will very much affect our lifestyle. Dementia and other cognitive dy…
Neelam Pawar, Pawan Jalwal
pp. 260-268 · DOI: 10.5530/ijpi.2021.3.46 · 2021
The medicine was given to the target site with a pressurized topical spray (aerosol pharmaceutical) and a non-pressurized topical spray solution by gently pressing the spray container against the skin and initiating the …
Original Article
Maryam Bazi, Davoud Balarak, Aram Dokht Khatibi, Shaziya Haseeb Siddiqui, Ferdos Kord Mostafapour
pp. 269-273 · DOI: 10.5530/ijpi.2021.3.47 · 2021
Background: Improper use of antibiotics and their discharge into the environment have serious and dangerous consequences. About 30-30% of antibiotics are not metabolized in the body and enter the environment through urin…
Sinta Khairunnisa, Harmita H, Herman Suryadi
pp. 274-277 · DOI: 10.5530/ijpi.2021.3.48 · 2021
Objectives: This study aimed to obtain an optimum method for zincyeast production. Materials and Methods: Production of zinc-yeast was prepared using Yeast Extract Peptone Dextrose (YEPD) as a culture medium. Yeast that …
Nur Azizah, Harmita H, Herman Suryadi
pp. 278-282 · DOI: 10.5530/ijpi.2021.3.49 · 2021
Objectives: The objective of this study was to perform selenium yeast production and analyze the selenium and protein contained in selenium yeast obtained. Methods: Selenium yeast production was carried out by incubating…
Kaushlendra Pratap Singh, Sachin Kumar
pp. 283-287 · DOI: 10.5530/ijpi.2021.3.50 · 2021
Objectives: The principal objective of this research is to fabricate, characterize and in vitro evaluation of floating gastroretentive Dicyclomine Hydrochloride beads. Methods: In this study, Ionotropic gelation technolo…
Hasan Pasha Nazeer Ahmed Sholapur, Fatima Sanjeri Dasankoppa, Mudlapur Channabasavaraja, Revati Dharampal Sagare, Zaheer Abbas, Nanjangud Gangadhariah Nanjunda Swamy, Lakshmi Swapna Sai, Kamaladevi Kshatriya
pp. 288-295 · DOI: 10.5530/ijpi.2021.3.51 · 2021
Background: The goal of this research was to use the Quality by Design (QbD) approach to develop orally disintegrating tablets of Montelukast sodium, a leukotriene receptor antagonist used to treat asthma. Characterizing…
Laya Dudi, Narayani Vadhuka Jillellamudi, Chandrasekhar Chanda, Giridhar Kanuri
pp. 296-299 · DOI: 10.5530/ijpi.2021.3.52 · 2021
Objectives: Edible oils, derived from a plant source, play a vital role in providing nutrition. A quality edible oil has a flavor, range of physicochemical parameters. Several quality parameters like saponification value…
Ravi Kumar Pola, Srinu Naik Sapavatu, Madhava Reddy Bommineni
pp. 300-305 · DOI: 10.5530/ijpi.2021.3.53 · 2021
Objectives: Molecular docking studies are efficient tools to study the biopharmaceutical and pharmacokinetic parameters of drug compounds. The present study aimed to determine the in-vitro cytotoxic activity of stem bark…
Ajay Kumar, Manmath Kumar Nandi, Brijesh Kumar, Ashutosh Kumar, Rajesh Kumar, Ambrish Kumar Singh, Manish Singh
pp. 306-311 · DOI: 10.5530/ijpi.2021.3.54 · 2021
Background: Urolithiasis, commonly known as nephrolithiasis, kidney stone, or renal stone, is a disorder caused by a decrease in anti-oxidant capability, damaged renal epithelium or consistently supersaturated urine, whi…
Seema Thakur, Haritha Pasupulati, Shrinivas Krishnarao Kulkarni, Satyanarayana Siddhi Venkata Padi
pp. 312-318 · DOI: 10.5530/ijpi.2021.3.55 · 2021
Background: Neuropathic pain, a chronic debilitating painful condition, is frequently difficult to manage with the conventional analgesics. Emerging evidence indicates potential role of peroxisome proliferator-activated …
Ketan Kailash Khelwade, Shrikalp Deshpande
pp. 319-323 · DOI: 10.5530/ijpi.2021.3.56 · 2021
Background: Antibiotic-resistant infections have elevated rates of morbidity and mortality, and antibiotic exposure is a significant trigger factor for drug resistance growth. If surgical antibiotic prophylaxis (SAP) inc…
M Raghavendran, Tapti Bhattarcharjee, R Revathi
pp. 324-326 · DOI: 10.5530/ijpi.2021.3.57 · 2021
Background: Errors during medication administration shows alarming frequency in hospital environment majorly in the areas like emergency, critical care etc. The process of medication administration used in hospital setti…
Rizwana Parveen, Prem Kapur, Nidhi Bharal Agarwal
pp. 327-332 · DOI: 10.5530/ijpi.2021.3.58 · 2021
Background: Type 2 diabetes mellitus (T2DM) is linked to a significant rate of depression and cognitive impairment, according to previous studies. However, limited research has been done on the effects of diabetes treatm…
Amar Prashad Chaudhary, Adna Nelson K, S Mydhily, Chaithanya KJ, Jamuna TR
pp. 333-337 · DOI: 10.5530/ijpi.2021.3.59 · 2021
Background: The promotion of generic medicines in developing nation like India plays a crucial role in the availability of essential drugs for everyone. The main objective of this survey is to understand the knowledge an…
Mohammad Javad Mehran, Basaralu Yadurappa Sathish Kumar, Nanjundappa Haraprasad, Rambod Barzigar, Bashasab Fakrudin, Sayan Paul
pp. 338-344 · DOI: 10.5530/ijpi.2021.3.60 · 2021
Background: Plant biotechnology revolutionized the branch of plant sciences contributing to improving crop production. Helicobacter pylori was predominantly seen among all the sectors of the human population, closely stu…