International Journal of Pharmaceutical Investigation · Archive
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In this issue
1–20 of 38Review Article
Sai Madhav Peddibhotla, Aishwarya Nair, Anju Joby
pp. 268-272 · DOI: 10.5530/ijpi.14.2.34 · 2024
Halotherapy is the use of dehumidified oxygen or salt aerosol microparticles attached to a face to treat pulmonary conditions. It was first reported as a substitute to oxygen masks for speleotherapy, a healing technique …
Sarojini Nayak, Druga Madhab Kar, Saroj Kumar Choudhury, Manoj Kumar Dalai
pp. 273-288 · DOI: 10.5530/ijpi.14.2.35 · 2024
Polygonum plebeium R. Br. (Family: Polygonaceae) is commonly known as “small knotweed”. It is used as a traditional medicine by many cultures across the world. In the rural communities of Shahjahanpur, Uttar Pradesh, it …
Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Viswanatha Swamy, B J Abhishek, Leena Elizabeth Varghese, S K Bhoomika
pp. 289-298 · DOI: 10.5530/ijpi.14.2.36 · 2024
This review explores the evolution of the concept of Healthcare-Associated Pneumonia (HCAP) in light of the 2016 guidelines from the Infectious Diseases Society of America (IDSA). These updated guidelines prioritize pati…
Sonal Jesa Dsouza, DS Sandeep, R Narayana Charyulu, MP Gowrav, HK Pradeep
pp. 299-305 · DOI: 10.5530/ijpi.14.2.37 · 2024
Impurities are undesired chemical substances found in pharmaceutical drug products with no therapeutic benefits and, in some cases, can pose a risk to patient safety if their levels exceed a certain limit. Impurities pre…
Varadarajan Sathiya, V Ramesh Kumar
pp. 306-316 · DOI: 10.5530/ijpi.14.2.38 · 2024
Studying the immunogenicity of insulin is crucial for managing and treating diabetes and other medical conditions. Although insulin therapy is proven effective for diabetic patients, the presence of insulin antibodies ca…
Gopinath Subramaniyan, Shaik Rubina, Bachu Venkata Ramana, A. Meriton Stanley, Devasena Srinivasan
pp. 317-326 · DOI: 10.5530/ijpi.14.2.39 · 2024
Background: The growing popularity of transdermal patches is attributed to their advantageous characteristics, including the absence of gastric-related problems, prolonged drug release, enhanced safety and stability, and…
Vaibhav Rastogi, Mayur Porwal, Anurag Verma, Umair Khan, Prabal Chauhan, Prashant Kumar
pp. 327-337 · DOI: 10.5530/ijpi.14.2.40 · 2024
Recurrent Aphthous Stomatitis (RAS) is a condition characterized by the development of ulcers and lesions, in the mouth. It affects a wide portion of the population ranging from 5% to 25%. RAS more commonly affects labia…
B. Kishore Babu
pp. 338-342 · DOI: 10.5530/ijpi.14.2.41 · 2024
Personalized medicine, driven by advancements in pharmacology, is revolutionizing healthcare by tailoring medical treatments to the unique characteristics of individual patients. This paradigm shift from a generalized ap…
Original Article
Ashwini Somayaji, Chakrakodi Shashidara Shastry
pp. 343-349 · DOI: 10.5530/ijpi.14.2.42 · 2024
Objectives: The purpose of this study was to assess the potential synergistic and chemo sensitizing effects of the plant-derived flavonoid EGCG (Epigallocatechin gallate) as an adjuvant therapy with doxorubicin in combat…
Rohit Jaysing Bhor, Wayse Siddheshwar Sunil, Rahul Bapusaheb Shirole, Karan Suresh Kadam, Santosh Dighe, Mahesh Hari Kolhe
pp. 350-358 · DOI: 10.5530/ijpi.14.2.43 · 2024
Background: A heterocyclic hydrocarbon having a 5, 5-diphenylimidazolidine heterocyclic ring that possesses distinctive fundamental structural characteristics. It is a fused ring of aromatic di-benzene and imidazolidine.…
Farzana Sadaf, Sumbul Shamim, Humera Ishaq, Ata-ur- Rehman, Ishrat Younus, Faheema Siddiqui
pp. 359-364 · DOI: 10.5530/ijpi.14.2.44 · 2024
Background: High Blood Pressure (BP) is a dreadful condition worldwide. Available scientific data confirms the antihypertensive potential of traditional plants. Present study was aimed to assess the blood pressure loweri…
Navid Naghsh, Shiva Barnoos, Fatemeh Zisti, Kethineni Chandrika, Davoud Balarak
pp. 365-370 · DOI: 10.5530/ijpi.14.2.45 · 2024
Background: The development of micro-organism resistance in humans and the environment has been linked to the inadequacy of conventional treatment methods in completely eliminating antibiotics. The purpose of this resear…
Sk. Mehatab Unnisa, Sana Seereen, Jampana Lekhana, Goreti Archana, Annam Hemanth Kumar, Soma Mani Santhosh Nikhil, Maram Chinnaeswraiah
pp. 371-377 · DOI: 10.5530/ijpi.14.2.46 · 2024
Background: The most prevalent lifestyle diseases are Diabetes Mellitus type 2 (DM2) and Hypertension (HTN), especially in older age groups, which leads to Chronic Kidney Disease (CKD) as the most possible comorbidity. M…
Rajesh Hadia, Nishee Chhatbar, Priyanka Padiya, Viram Shah, Siddhi Patel, Neel Shah, Hemraj Singh Rajput
pp. 378-385 · DOI: 10.5530/ijpi.14.2.47 · 2024
Background: Ureteric stones, characterized by the crystallization of mineral particles in stagnant urine, cause considerable discomfort and pain. Alpha-blockers are employed in the management of ureteric stones to allevi…
Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Viswanatha Swamy, Akshata M Purantar, Bibi Khuteja Jangliwale, Kaushal Kumar, T. P Rakshitha
pp. 386-391 · DOI: 10.5530/ijpi.14.2.48 · 2024
Background: Geriatric populations have at high probability of getting drug-related issues due to age-related pharmacokinetic and pharmacodynamic changes. Ageing populations are more prone to have DRPs due to age, drug ch…
Hezinglila Grace, D. Leelavathi, Kevizano Jacinta Zashumo
pp. 392-398 · DOI: 10.5530/ijpi.14.2.49 · 2024
Background: Staphylococcus aureus is an adaptive and versatile microorganism that can cause a wide range of ailments, from intense and short-lived infections to persistent infections that are difficult to cure. Even thou…
Devyani Rajput, Dharmendra Jain, Sushil Kumar Kashaw, Umesh Kumar Patil
pp. 399-408 · DOI: 10.5530/ijpi.14.2.50 · 2024
Background: Nyctanthes arbortristis Linn., popularly referred to as Parijat or Night-flowering Jasmine, has garnered significant attention in traditional medicinal practices owing to its wide-ranging array of phytochemic…
Duyu Taaza, Sunil S. Jalalpure, Basanagouda M. Patil, Bhaskar Kurangi
pp. 409-418 · DOI: 10.5530/ijpi.14.2.51 · 2024
Background: Olanzapine causes alterations in lipid and glucose metabolism, indicated by weight gain, and altered metabolic profiles. Hesperidin has been related to numerous positive health benefits including improvements…
M Ashwini, K P Kiran, Mamun Ahmed, A P Ravinandan, G Mohammed Mustafa
pp. 419-427 · DOI: 10.5530/ijpi.14.2.52 · 2024
Background: Clinical Pharmacy Services (CPSs) is a branch of health sciences which render patient care by optimizing pharmaceutical therapy and providing guidance to patient regarding health, medications and disease prev…
Nimmathota Madhavi, Balaga Divya, Beeravelli Sudhakar, Tadikonda Rama Rao
pp. 428-435 · DOI: 10.5530/ijpi.14.2.53 · 2024
Background: Mesalamine produces many side effects through oral route such as stomach cramps, throat irritation, back ache and muscle pain. Furthermore, it failed to yield maximum drug release and also not able to produce…