International Journal of Pharmaceutical Investigation · Archive
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In this issue
Review Article
Rajni Bala, Pravin Pawar, Sushil Khanna, Sandeep Arora
pp. 67-76 · DOI: 10.4103/2230‑973X.114897 · 2013
Recently, fast dissolving films are gaining interest as an alternative of fast dissolving tablets. The films are designed to dissolve upon contact with a wet surface, such as the tongue, within a few seconds, meaning the…
Original Research Article
Amit Mukharya, Paresh U Patel, Shivang Chaudhary
pp. 77-87 · DOI: 10.4103/2230‑973X.114903 · 2013
Introduction: Lacidipine (LCDP) is chemically a “1, 4‑dihydropyridine derivative” Ca+2 channel blocker used as an antihypertensive. Type and extent of packaging have a strong influence on the photo‑stability of the 1,4‑d…
Manju Nagpal, Shailendra Kumar Singh, Dinanath Mishra
pp. 88-94 · DOI: 10.4103/2230‑973X.114906 · 2013
Objective: Current research was aimed at the development of the drug delivery systems based on the superporous hydrogels (SPH) with the desired swelling and the mechanical properties. Materials and Methods: Superporous h…
Pranav V Patel, Hitesh K Patel, Shital S Panchal, Tejal A Mehta
pp. 95-104 · DOI: 10.4103/2230‑973X.114899 · 2013
Background: Tacrolimus has poor solubility in water ranging from 4 to 12 µg/mL. The oral bio availabilities of tacrolimus is poor and exhibits high intra and inter‑subject variability (4‑89%, average 25%) in the liver an…
Bhavik Bhatt, Marina Koland, K Prasanna Shama
pp. 105-111 · DOI: 10.4103/2230‑973X.114896 · 2013
Introduction: Iontophoresis was used to enhance the delivery of aceclofenac (ACF) from topical gels formulated with various polymers for the purpose of relieving pain and inflammation. Materials and Methods: Gels were fo…
Rachna Kumria, Vishant Gupta, Sanjay Bansal, Jyoti Wadhwa, Anroop B Nair
pp. 112-118 · DOI: 10.4103/2230‑973X.114894 · 2013
Introduction: Difficulty or inability in swallowing tablets/capsules during or after chemotherapy is common due to chemotherapy induced nausea and vomiting in patients. Buccoadhesive films of ondansetron hydrochloride we…