International Journal of Pharmaceutical Investigation · Archive
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In this issue
Editorial
- Article
Ramandeep Singh Narang, Jasjeet Kaur Narang
pp. 121-123 · DOI: 10.4103/2230-973X.160843 · 2015
Nanotechnology is directed at manipulating matter at the nanometer level and the application of the same to medicine is called nanomedicine. Over the past few years researchers have developed various nanomedicines for di…
Review Article
Charu Bharti, Upendra Nagaich, Ashok Kumar Pal, Neha Gulati
pp. 124-133 · DOI: 10.4103/2230-973X.160844 · 2015
Due to lack of specifi cation and solubility of drug molecules, patients have to take high doses of the drug to achieve the desired therapeutic effects for the treatment of diseases. To solve these problems, there are va…
Original Research Article
Mona Alibolandi, Fatemeh Sadeghi, Seyed Hossein Sazmand, Seyed Mohammad Shahrokhi, Mahmoud Seifi, Farzin Hadizadeh
pp. 134-141 · DOI: 10.4103/2230-973X.160846 · 2015
Introduction: The copolymer of polyethylene glycol (PEG) and polyesters has many interesting properties, such as amphiphilicity, biocompatibility, biodegradability, and self-assembly in an aqueous environment. Diblock co…
Pawan Kumar, Shailendra Kumar Singh, Dina Nath Mishra, Priti Girotra
pp. 142-146 · DOI: 10.4103/2230-973X.160850 · 2015
Introduction: Ketorolac tromethamine (KT), a nonsteroidal anti-infl ammatory drug, when given orally causes gastrointestinal disturbances. Its transdermal drug delivery may reduce such side effects associated with them. …
Manikandan Mahalingam, Kannan Krishnamoorthy
pp. 147-154 · DOI: 10.4103/2230-973X.160852 · 2015
Introduction: The objective of this investigation was to design and optimize the experimental conditions for the fabrication of camptothecin (CPT) loaded Eudragit S 100. Nanoparticles, and to understand the effect of var…
Deepak Sharma, Gilphy Philip, Reema Gabrani, Javed Ali, Shweta Dang
pp. 155-160 · DOI: 10.4103/2230-973X.160853 · 2015
Aim and Objectives: In the present investigation dual agents i.e., hesperidin and diazepam loaded polymeric nanoparticles (NPs) were formulated by nanoprecipitation method and optimized using three-level factorial design…
Priya Shahi, Neeraj Kumari, Kamla Pathak
pp. 161-170 · DOI: 10.4103/2230-973X.160854 · 2015
The objective of the present work was to develop a novel delivery system of ketorolac tromethamine (KT) for dual pulse release based on microspheres and tablet in capsule system (MATICS) as a treatment modality for rheum…
Adinarayana Gorajana, Adhiyaman Rajendran, Lee Mun Yew, Kamal Dua
pp. 171-178 · DOI: 10.4103/2230-973X.160857 · 2015
Aim: The objective of the current study is to increase the dissolution rate of cefuroxime axetil (CA) by formation of binary CA solid dispersion using water soluble carriers such as polyvinylpyrrolidone (PVP K30) and pol…