International Journal of Pharmaceutical Investigation · Archive
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In this issue
21–40 of 41Original Article(continued)
Arvind Raghav, Vaibhav Rastogi, Arulsamy Elphine Prabahar
pp. 1261-1267 · DOI: 10.5530/ijpi.20250308 · 2025
Background: An easy, quick, sensitive and precise extractive spectroscopic approach has been devised for the determination of lauric acid in pure form as well as present in virgin coconut oil. The approach is based on th…
Daniel Sundar Singh, Anand Pithadia, Lavanya
pp. 1268-1273 · DOI: 10.5530/ijpi.20250317 · 2025
Background: Cardiovascular disease is the major cause of morbidity and mortality in individuals with T2DM. Although many promising cardiac markers have been identified, a single Natriuretic peptide biomarker is unlikely …
Pratik Naveenkumar Magadum, Shivamantesh Ashok Kittur, Shashidhar Mallikarjun Javali, Gahana Lokeshwar, Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Viswanatha Swamy, B J Abhishek, Om Prakash Bhallaram Choudary, Aasiya Nadaf, Sachin Basavaraj, Srajana Shetty, Rakshita Paladi
pp. 1274-1280 · DOI: 10.5530/ijpi.20250320 · 2025
Background: Chronic Kidney Disease (CKD) is a global health issue characterized by a gradual decline in kidney function, often leading to reduced health-related quality of life (HRQoL). Despite CKD affecting 8-16% of the…
Akshata Gore, Arfa Anwar Sayed, Shamita Shyam Sail, Ramish Khan, Agadi Hiremath Viswanatha Swamy, Sanatkumar Bharmu Nyamagoud
pp. 1281-1287 · DOI: 10.5530/ijpi.20250325 · 2025
Background: Medical devices are used vitally in the healthcare system. Since India is a developing country, it didn’t have a valid outline to screen and notice the adverse events occurred using medical devices. Hence, ma…
Arfa Anwar Sayed, Akshata Gore, Shamita Shyam Sail, Ramish Khan, Agadi Hiremath Viswanatha Swamy, Sanatkumar Bharmu Nyamagoud
pp. 1288-1297 · DOI: 10.5530/ijpi.20250326 · 2025
Background: The Materiovigilance Programme of India (MvPI) was launched on 6th July 2015 by the (DCGI) at the Indian Pharmacopoeia Commission, to ensure the safety and effectiveness of medical devices. With the increasin…
Om Prakash Bhallaram Choudary, Aasiya Nadaf, Pratiksha Bajarang Bhandare, Agadi Hiremath Viswanatha Swamy, Sanatkumar Bharamu Nyamagoud, Abhishek B J, Pratik Naveenkumar Magadum, Shivamantesh Ashok Kittur, Chandrashekar Mallikarjun Patil, Vinod Ashok Koujalagi
pp. 1298-1303 · DOI: 10.5530/ijpi.20250333 · 2025
Background: Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder in young women, marked by hormonal imbalances, insulin resistance, and elevated androgens. Each of these factors causes medical conditions such …
Akshata Manjunath Purantar, Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Viswanatha Swamy, Bibi Khuteja Jangliwale, Kaushal Kumar, Rakshita T P
pp. 1304-1310 · DOI: 10.5530/ijpi.20250334 · 2025
Background: Older adults are at a higher risk of experiencing drug-drug interactions due to their tendency to use several medications simultaneously, which may include prescription medications, over-the-counter products …
Yogita Shinde, Gitanjali Deokar
pp. 1311-1319 · DOI: 10.5530/ijpi.20250345 · 2025
Introduction: The demand for natural excipients in pharmaceuticals has driven interest in plant-based materials. Lepidium sativum seed mucilage, a polysaccharide-rich and biocompatible compound, shows promise as a tablet…
Anchal Kushwaha, Kandasamy Nagarajan, Richa Goel, Garima Kapoor, Snigdha Bhardwaj, Pankaj Bhatt
pp. 1320-1331 · DOI: 10.5530/ijpi.20251665 · 2025
Background: Olmesartan (OLM) is a drug used to treat hypertension, or elevated blood pressure. Controlling high blood pressure lowers the chance of further strokes, renal problems and heart attacks. Materials and Methods…
Kadambari Solankure, Vinod Gurav, Usharani Sanu, Nayana Bhagat, Eksheka Mall
pp. 1332-1339 · DOI: 10.5530/ijpi.20250294 · 2025
Background: Prakriti is a unique concept, which exceptionally finds its presence in Ayurveda. It is the unique psychosomatic constitution of an individual, constituted on the basis of the innate qualities of the matruja …
Vibha, Shiv Bahadur, Meenakshi Bajpai
pp. 1340-1347 · DOI: 10.5530/ijpi.20250272 · 2025
Introduction: Wounds may be known as any damage or distortion to the normal structural and functional of skin, if left untreated it can be more dangerous, reaching in subcutaneous tissue and serious harm to other structu…
Anuj Kumar, Anurag Verma
pp. 1348-1359 · DOI: 10.5530/ijpi.20250312 · 2025
Background: In situ forming dental cements offer a novel approach to treating periodontitis by enabling localized delivery of therapeutic agents directly to the periodontal cavity. Hydroxyapatite-based materials hold pro…
Bolleddu Ravi, Thangallapalli Srinivas, Kuntla Raj Kumar, Mannepalli Sudheera
pp. 1360-1364 · DOI: 10.5530/ijpi.20250007 · 2025
Aim/Background: Micro-channels, characterized by their minuscule size ranging from 10 µm to 200 µm, find diverse applications across various fields such as biomedical, electronics, and chemical reactors, etc. Here, it wa…
Swarna Lekha Suresh Gandhi, Anitha Rajasekaran, Harika Manniam Saravanabava, Munusami Angusami
pp. 1365-1369 · DOI: 10.5530/ijpi.20250008 · 2025
Background: Melatonin (N-acetyl -5- methoxy-tryptamine) is a mammalian neuro hormone, with numerous biological functions found in animals, plants, microorganisms and one of the extensively used dietary supplements. Phyto…
Kezia Mangalampalli, Aravinda Sai Kolusu, Hrushik Kowtinya Ramineni, Harshitha Mudigonda, Surya Devarakonda, Pavan Kumar Samudrala
pp. 1370-1379 · DOI: 10.5530/ijpi.20250009 · 2025
Background: Cholinergic neurons in the brain and hippocampus appear to be most affected in the early stages of Alzheimer's Disease (AD). Cognitive impairment has been induced in rodents for many years with the muscarinic…
Jamith Basha Abdul Wahid, Mohameed Aljuwayd, Muhannad Alruwaili, Wesam Nofal
pp. 1380-1387 · DOI: 10.5530/ijpi.20250304 · 2025
Background: Nutritional modifications arise from an enhanced understanding of the importance of food and its impact on human well-being. Objectives: This study investigates the fermentation-based preservation of edible m…
Vinay Kumar Srivastava, Khushboo Rani
pp. 1388-1395 · DOI: 10.5530/ijpi.20250102 · 2025
Objectives: Cysteine is a promising ligand for synthesizing complexes with Mn (II) and Cu (II) ions. The main objectives of the study were to synthesize, characterize and examine the Biochemical behavior of metal complex…
Tejas Vyas, Ujashkumar Shah, Jayvadan Patel, Mrityunjay Tiwari
pp. 1396-1402 · DOI: 10.5530/ijpi.20250407 · 2025
Background: Ascorbic acid and gallic acid are known for immune-boosting and antioxidant properties. Objectives: To develop a straightforward, sensitive, validated, and economical reverse phase liquid chromatographic tech…
Vakkalagadda Siva Ganesh, Bharathi Doddla Raghunathanaidu
pp. 1403-1408 · DOI: 10.5530/ijpi.20250545 · 2025
Background: 11β-hydroxylase plays a key role in adrenal steroid hormone production, making it crucial in the development of adrenal insufficiency. Recently, there has been increasing interest in targeting this enzyme to …
Pratibha Yadav, Kamal Shah
pp. 1409-1416 · DOI: 10.5530/ijpi.20250577 · 2025
Objectives: To investigate the mechanism of pyridopyrimidines derivatives against monopolar spindle1 anticancer target and also predicts the pharmacokinetics parameters involved absorption, distribution, metabolism, elim…